The Fire Safety, Thermal and Fluids Engineering Area is an interdisciplinary research group of the IIT focused on the study and analysis of fire dynamics, from an experimental and numerical point of view. We develop mathematical models that allow the simulation of a wide variety of problems, thus addressing the effect of fire in fields such as structural mechanics, through the analysis of the behavior of different types of materials (steel, concrete, wood, adhesives, etc.), as well as in the field of fluid mechanics, by evaluating the behavior of the smoke and the flame. In addition, we use statistical methods to treat data and thus propose predictive models of the effects that different fire scenarios can generate. We present novel solutions in the design of fire protection systems, performance based designs, supported both by the knowledge of fire dynamics, and by numerical models of fire and structures. The Fire Safety, Thermal and Fluids Engineering Area collaborates with other research centers and associations, trying to promote this specific sector within the Engineering.