Conference paper information

Information-Geometric Selection in T-Cell Receptor Cascades How Noise Shapes Ligand Discrimination

J. Iribas-De-la-Puerta, M. Castro

XXVI Congreso de Física Estadística - FisEs'26, Tarragona (Spain). 14-16 October 2026

Spanish layman's summary:

Las células T deben distinguir en segundos antígenos peligrosos de inofensivos. Este trabajo modela la señalización del receptor como un proceso de inferencia bayesiana y muestra que existe una duración óptima del contacto celular que maximiza la información y afina la discriminación.

English layman's summary:

T cells must tell harmful from harmless antigens within seconds. This work models receptor signalling as Bayesian inference and shows there is an optimal contact duration that maximises information and sharpens discrimination between similar ligands.

Publication date: 14-Oct-2026.

Citation:
J. Iribas-De-la-Puerta, M. Castro, "Information-Geometric Selection in T-Cell Receptor Cascades How Noise Shapes Ligand Discrimination", presented at XXVI Congreso de Física Estadística - FisEs'26, Tarragona, Spain, 14-16 October 2026

Research topics:

Mathematical Models and Artificial Intelligence in Healthcare
Probabilistic Artificial Intelligence and Bayesian Inference
Mathematical and Causal Models

Research groups:

Instituto de Investigación Tecnológica (IIT)
Dinámica No Lineal

ODS:

Goal 3: Health and well-being

IIT-26-278C_poster

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