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Simultaneous determination of dexamethasone and betamethasone in pharmaceuticals by reversed-phase HPLC

A. Santos-Montes, A.I. Gasco-Lopez, R. Izquierdo-Hornillos

Chromatographia Vol. 39, nº. 9-10, pp. 539 - 542

Resumen:

An HPLC method for the simultaneous determination of the glucocorticoids betamethasone and dexamethasone is described. The method based on the separation of these compounds using a binary watertetrahyddrofuran mobile phase and a reversed-phase Hypersil C18 column, was applied to the determination of betamethasone and dexamethasone in tablets.


Palabras Clave: Column liquid chromatography; Glucocorticoids; Betamethasone and dexamethasone; Pharmaceuticals; Tablet preparations;


Índice de impacto JCR y cuartil WoS: 1,700 - Q4 (2022)

Referencia DOI: DOI icon https://doi.org/10.1007/BF02268276

Publicado en papel: Noviembre 1994.



Cita:
A. Santos-Montes, A.I. Gasco-Lopez, R. Izquierdo-Hornillos Simultaneous determination of dexamethasone and betamethasone in pharmaceuticals by reversed-phase HPLC. Chromatographia. Vol. 39, nº. 9-10, pp. 539 - 542, Noviembre 1994.


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